IRF5-KO/NFκB-SEAP/THP-1
CBP74212
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| I. Background | |
| IRF5 (Interferon Regulatory Factor 5) is a Protein Coding gene. Diseases associated with IRF5 include Systemic Lupus Erythematosus 10 and Inflammatory Bowel Disease 14. | |
| II. Introduction | |
| Host Cell: | THP-1 |
| Expressed gene: | IRF5-KO |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+2 mM L-glutamine+25 mM HEPES+10%FBS+100 U/ml penicillin+100 µg/ml streptomycin+100 µg/ml Normocin |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Homo sapiens, human |
| Tissue: | peripheral blood |
| Disease: | acute monocytic leukemia |
| Morphology: | monocyte |
| Growth Properties: | suspension |
| IV. Representative Data | |