hROR1/CHO
CBPG0100
詢(xún) 價(jià)
留 言
產(chǎn)品描述
產(chǎn)品數據庫
| I. Background | |
| 受體酪氨酸激酶樣孤兒受體(Receptor Tyrosine Kinase-like orphan receptor,ROR)是 Ⅰ型受體酪氨酸激酶(receptor tyrosine kinase,RTK)家族中的成員,是一類(lèi)膜受體,主要 包括 ROR1 和 ROR2。其中 ROR1 主要通過(guò)參與細胞內與細胞間信號傳導,實(shí)現調節細胞 代謝、增殖、凋亡、分化、遷移、轉移等功能。ROR1 在正常組織中(除了原腸胚時(shí)期) 表達量較低,但 ROR1 在多種腫瘤細胞高度表達,包括乳腺癌、卵巢癌、腎癌、肺腺細胞 癌、胃癌等實(shí)體瘤細胞以及某些血液腫瘤細胞。 | |
| II. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | hROR1 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5μg/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Hamster |
| Tissue: | Ovary |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| IV. Representative Data | |
|
Figure 1. Recombinant hROR1/CHO stably expressing hROR1. |
|
