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首頁(yè) /藥靶模型 /信號調控 /質(zhì)粒 /pCBRG-ETS-1 RE

pCBRG-ETS-1 RE

CBV20054

產(chǎn)品描述
產(chǎn)品數據庫
Introduction
Description: pETS-1 RE-Luc is designed for monitoring the induction of protein C-ets-1 responese element.They bind the DNA via their winged-helix-turn-helix DNA binding motif known as the Ets domain that specifically recognizes DNA sequences that contain a GGAA/T core element. However, Ets proteins differ significantly in their preference for the sequence flanking the GGAA/T core motif. For instance, the consensus sequence for Ets1 is PuCC/a-GGAA/T-GCPy. On the other hand, many natural Ets1-responsive GGAA/T elements differ from this consensus sequence. The later suggests that several other transcription factors may facilitate Ets1 binding to unfavorable DNA sequences.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): Protein C-ets-1
Pathway profile:
Full Name: Protein C-ets-1
Cis response element: ETS-1 RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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