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首頁(yè) /科研細胞 /人源細胞系 / /SNU-398(人肝癌細胞)

SNU-398(人肝癌細胞)

CBP60215

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I. General information 
Synonyms: SNU-398
Background: SNU-398 was derived in 1990 by J.-G. Park and associates from an anaplastic hepatocellular carcinoma taken from a Korean patient who had been treated by transcatheter arterial embolization with lipoidol plus a combination of doxorubicin and mitomycin-C.
Tumor cells were initially cultured in ACL-4 medium supplemented with 5% heat-inactivated fetal bovine serum. After establishment, cultures were maintained in RPMI 1640 supplemented with 10% heat inactivated fetal bovine serum.
Species: Homo sapiens, human
Tissue: liver
Disease: hepatocellular carcinoma
Gender: male, 42 years,  Asian
Morphology: epithelial
Growth Mode: mixed adherent and floating
Doubling Time: 39 hrs
DNA Profile: Amelogenin: X,Y
CSF1PO: 13
D13S317: 11
D16S539: 10,14
D5S818: 12
D7S820: 10,11
THO1: 7,9
TPOX: 11
vWA: 17,18
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Culture Medium:

RPMI-1640+10%FBS

SNU-398完全培養基,# CBP60215M
We strongly suggest to purchase the complete medium from us.

Cryopreservation medium: 90%FBS+10%DMSO
Antigen Expression: Blood Type O; Rh +
Comments: Grossly, the original tumor was single nodular with perinodular extensions.
Histologically, it was trabecular type.
The cultured cells are multinucleated, and maintain the production of intracytoplasmic hyaline globules as seen in the original tumor.
Hepatitis B virus (HBV) DNA was detected by Southern blot hybridization.
HBV genomic RNA was not expressed.
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